Tag Archives: research

National Football League Veteran Wes Chandler Creates WCTE Inc. to Tackle Chronic Traumatic Encephalopathy

Former NFL player, Wes Chandler, a member of the San Diego Chargers Hall of Fame, and most recently an inductee into the College Football Hall of Fame, announced today the formation of a biotechnology company named WCTE Inc. which is dedicated to the diagnosis, intervention, and cure of Chronic Traumatic Encephalopathy (CTE).

At present, the formal diagnosis of CTE can only be made after death, and there is currently no treatment available.  CTE is the cause of depression and suicide in numerous football players, according to Chandler, founder and CEO of WCTE.

“WCTE Inc. was formed because of the urgent unmet need to treat my friends and colleagues, who have sacrificed their health and their lives for popular entertainment.  Now that they need our help, it is our responsibility to be there for them,” said Chandler, who was a star receiver at the University of Florida before moving on to the NFL.  “It is my vision to identify, integrate and incorporate the latest technologies in order to provide a fighting chance for my colleagues.”

CTE has been understudied in contrast to other types of brain injuries, resulting in a time sensitive opportunity for development of intellectual property and therapies in this relatively unexplored area, according to Chandler.  In addition to the estimated $2 billion CTE market, technologies developed addressing CTE possess potential to address the substantially larger Alzheimer’s and aging market.

The company’s immediate focus falls upon three areas. First, capturing all intellectual property related to CTE through licensing/filing of patents.  Secondly, obtain ID approval to initiate a CTE clinical trial using its clinical state stem cell product WesCellTM.  Lastly, generating revenue through sales of NeuroStilbeneTM.

Assisting Chandler in organization of WCTE is Dr. Thomas Ichim, a successful biotechnology entrepreneur whose career successes include taking a stem cell company from discovery of the stem cell to FDA clearance, to sale of the company; 121 peer reviewed papers; 130 patents and patent applications; and successful development of 5 cellular therapeutics that have entered the clinic.

“I am honored to work with Mr. Chandler on helping find a cure for his colleagues and others who suffer from this devastating condition. Having known Wes for several years, I can attest he brings a fresh, multi-disciplinary, goal-oriented, approach to biotechnology. I look forward to working with him in identifying, licensing, and developing key technologies useful for treatment of CTE,” said Dr. Thomas Ichim.

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Consensus Statement on Sports-Related Concussions in Youth Sports Using a Modified Delphi Approach

A recent paper by JAMA Pediatrics seems to support that notion. The purposes of the paper was to review the “rapid progress of research on this topic over the last decade, and the need to provide further guidance to youth athletes, their families, medical professionals, and athletic personnel and organizations.” To do that, “a panel of experts undertook a modified Delphi consensus process to summarize the current literature and provide recommendations regarding the prevention, assessment, and management of sports-related concussions for young athletes.”

Abstract

Importance  Given the importance of sports-related concussions among youth athletes, the rapid progress of research on this topic over the last decade, and the need to provide further guidance to youth athletes, their families, medical professionals, and athletic personnel and organizations, a panel of experts undertook a modified Delphi consensus process to summarize the current literature and provide recommendations regarding the prevention, assessment, and management of sports-related concussions for young athletes.

Methods  A consensus panel of 11 experts was created to represent a broad spectrum of expertise in youth sports and concussions. The specific questions to be addressed were developed through an iterative process consisting of 3 rounds, and a review of the literature was conducted to identify research studies related to each question. The consensus panel used a modified Delphi process to reach consensus on the conclusions and recommendations for each question.

Results and Conclusions  In 3 Delphi consensus rounds, 7 questions were addressed by the consensus panel of 11 experts, and 26 recommendations for the prevention, assessment, and management of sports-related concussions among young athletes were developed. For many of the questions addressed in this consensus statement, limitations existed in the quantity and quality of the evidence available to develop specific recommendations for youth sports stakeholders.

To get the full paper, visit: https://jamanetwork.com/journals/jamapediatrics/article-abstract/2754823

 

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NFL Announces Winners of Second Head Health Tech Challenge

The National Football League (NFL) and Football Research, Inc. (FRI) today announced the winners of HeadHealthTECH Challenge II, which invited proposals for improvements in football protective equipment including helmets and related technologies, turf systems, shoulder and other pads, and additional innovative concepts.

Launched in November 2016, the TECH Challenge series is operated and managed on behalf of FRI by Duke University’s Clinical and Translational Science Institute (Duke CTSI).

“The TECH Challenge series is designed to identify promising innovations that improve sports safety,” said Jeff Miller, NFL Executive Vice President of Health and Safety Initiatives. “This effort not only provides finalists with needed funding to advance these technologies, but all of those who submit proposals also receive invaluable mentorship and feedback from our partners at Duke CTSI.”

FRI awards the most promising TECH Challenge proposals with a cumulative value of up to $1 million a year, including in-kind support. For TECH Challenge II, a panel of expert judges selected by Duke CTSI, in collaboration with FRI, reviewed and provided feedback on 85 proposals all focused on improved protective equipment. Every TECH Challenge applicant is invited to reapply and receives constructive feedback from Duke CTSI biomechanical experts to help refine innovations and increase chances for success on future submissions.

TECH Challenge II Winners:

  • 2ND Skull—Pittsburgh, PA— received a grant of $100,000 to further evaluate the effectiveness of the 2nd Skull® skull cap in reducing impact forces and developing a second-generation version.
  • Baytech Products—Asheville, NC— received a grant of $178,000 to build and test its prototype HitGard® multi-component helmet system concept.
  • Windpact—Leesburg, VA— received a grant of $148,000 to support prototyping and testing of its Crash Cloud™, an impact liner system using restricted air flow and foam in helmets and protective gear.

“We want to help these and all innovators who participate in the TECH Challenges to succeed—stimulating the marketplace and raising the bar for sports safety,” said Barry Myers, MD, PhD, MBA, Director of Innovation Duke CTSI, Coulter Program Director and Professor of Biomedical Engineering at Duke University and a consultant to the NFL Players Association (NFLPA). “We’re excited about the technologies that surfaced in TECH Challenges I and II, and look forward to discovering and advancing even more innovations with TECH Challenge III.”

The HeadHealthTECH Challenge series is one component of the Play Smart. Play Safe. Engineering Roadmap—a $60-million comprehensive plan funded by the NFL and managed by FRI to create incentives for sporting goods companies, as well as other manufacturers, small businesses, entrepreneurs, and universities from around the world to develop improved helmets and protective equipment in the next two to four years.

TECH Challenge III is open for submissions through September 29, 2017. Information about TECH Challenges and the process for making a submission can be found at:www.PlaySmartPlaySafe.com/HeadHealthTECH. TECH Challenge III winners are expected to be announced in early 2018.

Winners of TECH Challenge I, announced in April 2017, include VyaTek Sports for its highly efficient energy-absorbing Zorbz technology and Guardian Innovations for its Guardian Cap technology—a soft helmet cover designed to reduce the severity of impacts.

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